Chinese scientists find possible medicine for SARS

Published: 28 August 2005 y., Sunday

Scientists announced a possible breakthrough in the treatment of severe acute respiratory syndrome (SARS) on Friday.

    According to their report in Guangzhou, South China's Guangdong Province, small interfering Ribonucleic Acid (siRNA), able to target specific genes, is showing efficiency in combating the disease.

    SARS, first recognized in 2002, killed 774 people worldwide before it was brought under control by quarantine, isolating patients and restricting travel.

    Since then, researchers led by Zhong Nanshan, director of the Guangzhou Institute of Respiratory Diseases, have been working to find drugs and vaccines to prevent another outbreak.

    Researchers tested two types of siRNA that target different parts of the genome of the SARS virus.

    Tests on monkeys showed that, although animals treated with the siRNA could still be infected with the disease, their symptoms were significantly less severe, suffering less lung damage and smaller increases in body temperature.

    "The long-term experiments show that siRNA is effective in curing SARS, and the monkey subjects showed no adverse side effects," Li Baojian, a biotechnology professor of Zhongshan University, said on Friday.

    But, Zhong Nanshan added: "The technology of siRNA cannot be used clinically in the short term."   

Šaltinis: news.xinhuanet.com
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