President Fernando De la Rua submitted his resignation Thursday, a high-ranking official said, as his government crumbled amid deadly rioting and looting sparked by anger over Argentina's deepening economic crisis.

The resignation followed two days of clashes between police and protesters that left at least 20 people dead and scores injured. On Thursday, police battled hundreds of demonstrators in the streets of ArCongress before taking effect, officials said. Senate President Ramon Puerta was expected to be named interim president when the resignation is finalized. The official, who spoke with The Associated Press on condition of anonymity, said De la Rua had signed his resignation late Thursday afternoon. It came amid local reports that De la Rua efforts to cobble together a government of "national unity" with the opposition Peronist Party had encountered resistance. Earlier Thursday, De la Rua sent riot police to quell the violence after 20 people died across the country in two days of rioting sparked by the government's failure to end a punishing recession marked by double-digit joblessness, hunger and rising poverty. Authorities arrested more than 2,000 people nationwide, including 350 in the capital. In Buenos Aires, one man was dragged by his hair, others carried kicking and shouting to police vans. De la Rua's resignation came hours after his economy minister, Domingo Cavallo, quit. Television reports said the entire Cabinet had offered to resign.